ELM detail for MOD_CK2

MOD_CK2_1 64

Functional site class:	CK2 Phosphorylation site
Functional site description:	Motif recognised by CK2 for Ser/Thr phosphorylation
ELMs:	MOD_CK2_1
Description:	The main determinant of CK2 phosphorylation specificity is a negative charge 3 positions after the modification residue
Pattern:	`...([ST])..E` (Probability: 0.0145681)
Present in taxons:	Drosophila melanogaster Eukaryota Saccharomyces cerevisiae Vertebrata Zea mays
Interaction Domain:	Pkinase (PF00069) Protein kinase domain (Stochiometry: 1 : 1)

Abstract

12/11/02

Biological Process:
Regulation Of Circadian Rhythm	0042752
Response To Uv	0009411
Wnt Receptor Signaling Pathway	0016055
Cellular Compartment:
Cytosol	0005829
Nucleus	0005634
Protein Kinase Ck2 Complex	0005956
Molecular Function:
Protein Kinase	0004672
Protein Kinase Ck2	0004682

8 GO-Terms:

10 Instances for MOD_CK2_1
(click table headers for sorting)

Sequence	Start	End	Subsequence	Instance Logic	PDB	Organism
IRS1_RAT	499	505	ATMGTSPALTGDEAAGAADL	true positive	---	Rattus norvegicus (Norway rat)
IRS1_RAT	96	102	DEHFAIAADSEAEQDSWYQA	true positive	---	Rattus norvegicus (Norway rat)
IRS1_HUMAN	327	333	PGSFRVRASSDGEGTMSRPA	unknown	---	Homo sapiens (Human)
IRS1_HUMAN	85	91	KNKHLVALYTRDEHFAIAAD	unknown	---	Homo sapiens (Human)
IRS1_HUMAN	96	102	DEHFAIAADSEAEQDSWYQA	unknown	---	Homo sapiens (Human)
VPU_HV1BR	49	55	DRLIERAEDSGNESEGEISA	true positive	---	Human immunodeficiency virus type 1 (BRU ISOLATE)
VPU_HV1BR	53	59	ERAEDSGNESEGEISALVEM	true positive	---	Human immunodeficiency virus type 1 (BRU ISOLATE)
PTEN_HUMAN	382	388	HYRYSDTTDSDPENEPFDED	true positive	---	Homo sapiens (Human)
XRCC1_HUMAN	520	526	PYAGSTDENTDSEEHQEPPD	true positive	---	Homo sapiens (Human)
XRCC1_HUMAN	515	521	ENGEDPYAGSTDENTDSEEH	true positive	---	Homo sapiens (Human)

Please cite: ELM - the database of eukaryotic linear motifs (PMID:22110040)

ELM data can be downloaded and distributed for non-commercial use according to the ELM Software License Agreement