The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003844 P08238 HSP90AB1
HS90B_HUMAN
252 258 EKPKIEDVGSDEEDDSGKDK TP --- Homo sapiens (Human) 724

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0256 rna interference in vivo Kim,2015 support certain InteractionDetection
experimental MI:0113 western blot in vitro Kim,2015 support certain ParticipantIdentification FeatureDetection
experimental MI:0586 inhibitor Kim,2015 support certain
experimental MI:0427 Identification by mass spectrometry Kim,2015 support certain ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P68400) CSK21_HUMAN PF00069 (Pkinase)
Protein kinase domain
39 324 [mitab][xml]

o  Pathways

KEGG: The sequence P08238 is implicated in the following 15 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM — the eukaryotic linear motif resource in 2020. (PMID:31680160)

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