| 18 Jan 2013 | ELM database updateNew classes have been added: CLV_Separin_Fungi, CLV_Separin_Metazoa, LIG_SUMO_SBM_1, LIG_SUMO_SBM_2, MOD_LATS_1, TRG_PEX_2, and TRG_PEX_3 and the following classes have been updated: LIG_Integrin_isoDGR_1, LIG_PCNA_PIPBox_1, and TRG_PEX_1. Many new Instances have been added to the database and links to external resources have been updated. Furthermore, information about interaction partners is shown at the instance detail page (where available). |
| 01 Aug 2012 | ELM database updateOne new ELM class has been annotated (LIG_SPRY_1) and existing ones have been updated: LIG_Integrin_isoDGR_1, TRG_PEX, LIG_Integrin_isoDGR_1, LIG_PCNA_PIPBox_1, LIG_CRL4_Cdt2_1, LIG_CtBP_PxDLS_1. Many new instances have been added to the database... |
| 11 Apr 2012 | ELM database updateOne new ELM class has been annotated (LIG_OCRL_FandH_1) and existing ones have been updated: LIG_14-3-3_3, LIG_PP1, LIG_TNKBM_1, LIG_WW_Pin1_4, MOD_TYR_ITAM, TRG_ER_diArg_1, and TRG_LysEnd_APsAcLL_1 |
| 02 Dec 2011 | ELM update paper publishedAll the latest updates and improvements have been written up in the latest ELM paper ( 22110040) |
| 02 Dec 2011 | ELM database updateNew ELM classes have been annotated:LIG_CAP-Gly_2, LIG_CRL4_Cdt2_2, LIG_CRL4_Cdt2_1, LIG_SCF_Skp2-Cks1_1, and CLV_C14_Caspase3-7 |
| 09 Nov 2011 | ELM sequences updateSequences of annotated ELM instances have been synced with UNIPROT.Instance positions were mapped onto new sequences. |
| 16 Oct 2011 | ELM database update
New ELM classes have been annotated: |
| 13 Sep 2011 | Re-Mapping of annotated experimental methodsAll experimental methods have been updated and synced to PSI:MI controlled vocabulary (where possible) |
| 05 Sep 2011 | New ELM Web InterfaceThe ELM resource got a new web interface:All HTML pages are now dynamically created using the python framework DJANGO; JavaScript is used to make the whole site more interactive and to communicate to the server via AJAX callbacks. The whole website was redesigned introducing many new features such as full-text search for ELM classes as well as instances. |
| 25 Aug 2011 | ELM database updateNew ELM classes have been annotated:LIG_EVH1_3, LIG_Actin_RPEL_3, LIG_Actin_WH2_2, LIG_Actin_WH2_1, LIG_AGCK_PIF_3, LIG_AGCK_PIF_2, LIG_AGCK_PIF_1, LIG_PAM2_1. |
| 20 Dec 2010 | ELM database updateThe list of ELM classes has been updated.New entries: LIG_BIR_III_4, LIG_FAT_LD_1, LIG_HCF-1_HBM_1, LIG_LYPXL_L_2, LIG_LYPXL_S_1, LIG_Rb_pABgroove_1 and LIG_SPAK-OSR1_1 Also, many new experimental instances have been added. |
| 08 Feb 2010 | ELM database updateThe list of ELM motif classes has been updated.New entries: LIG_BIR, LIG_GLEBS_BUB3, LIG_SCF-TrCP1, LIG_SCF_FBW7, LIG_SxIP_EBH, TRG_Cilium_Arf4, TRG_Cilium_RVxP, TRG_ER_FFAT, TRG_NLS_Bipartite, TRG_NLS_MonoCore, TRG_NLS_MonoExtC, and TRG_NLS_MonoExtN More than 100 new experimental instances have been added. |
| 02 Feb 2010 | New ELM candidate motif pageWe have created a page listing unannotated candidate motifs that might become ELM entries with your help. Please, feel free to browse this page and to annotate ELM with us. |
| 04 Dec 2009 | ELM Update imminentThe new ELM paper is out! New data and new motif entries are being finalised and will be added shortly to the ELM database. |
| 08 Apr 2009 | ELM Database UpdateNew entries for KEPE motifs. Also modifications to some existing entries e.g. 14-3-3 ligand motifs. |
| 02 Apr 2009 | ELM Structure Filter 1.1 addedAdditional functionality added. A p-value is assigned to each score of an ELM match. These p-values provide a conservative estimate of the probability that an ELM prediction with a given score is a true positive. |
| 19 Dec 2008 | ELM Structure Filter 1.0 addedRevised scoring scheme with better discrimination power, based on the non-wildcard positions of the linear motifs. |
| 07 Nov 2008 | ELM Database UpdateNew entries for Raptor, VHL, AP-2, TRF binder motifs. Also many mods to existing entries with new instances, improvements or corrections e.g. EH, Dbox. Inappropriate PIP2-binding structural motifs deleted. |
| 01 May 2008 | Linear Motif Review availableGet the open access linear motif review from FBS now |
| 12 Feb 2008 | ELM Structural Filter (BETA version) addedThe ELM Structural Filter evaluates the context of linear motifs lying within the query sequence, whenever a globular domain structure is available (≥70% similarity to the query sequence).The filter scores both the secondary structure overlap and the accessibility of the individual residues of each motif. |
| 13 Dec 2007 | ELM Database UpdateNew entries for PP2B, CAP-GLY, USP7, SIah. Experimental instances added to some existing entries e.g.PP1. |
| 09 May 2007 | ELM Database UpdateSubstantial update to the ELM database. Fixes to many existing entries. More than 10 new motif patterns e.g. NES, Destruction Boxes, MAP kinase docking motifs. |
| 26 Oct 2006 | ELM Database Web Service AvailableAs part of the EMBRACE project to integrate various European Bioinformatics resources, protein motif data stored in the ELM database can now be directly accessed through a Web Services schema. Users interested in using the WS are requested to contact the ELM Webmaster |
| 24 Jun 2005 | ELM instance mapper addedThe ELM instance mapper allow the identification of known experimental ELM instances in query sequences if annotated in the ELM resource.Additionally, predictions in sequences similar to annotated ELM instance sequences will be scored, if the motif position is conserved. |
| 25 Jun 2003 | ELM paper is outELM server: a new resource for investigating short functional sites in modular eukaryotic proteins.Puntervoll, P., Linding, R., Gemünd, C., Chabanis-Davidson, S., Mattingsdal, M., Cameron, S., Martin, D. M. A., Ausiello, G., Brannetti, B., Costantini, A., Ferrè, F., Maselli, V., Via, A., Cesareni, G., Diella, F., Superti-Furga, G., Wyrwicz, L., Ramu, C., McGuigan, C., Gudavalli, R., Letunic, I., Bork, P., Rychlewski, L., Küster, B., Helmer-Citterich, M., Hunter, W. N., Aasland, R., & Gibson, T. J. (2003). Nucleic Acids Res., 31: 3625-3630. |
Please cite: ELM - the database of eukaryotic linear motifs (PMID:22110040)
ELM data can be downloaded and distributed for non-commercial use according to the ELM Software License Agreement