The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003845 P05549 TFAP2A
AP2A_HUMAN
426 432 PNSHTDNNAKSSDKEEKHRK TP --- Homo sapiens (Human) 437

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0018 two hybrid in vivo Ren,2011 support certain InteractionDetection
experimental MI:0586 inhibitor Ren,2011 support certain
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Ren,2011 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ren,2011 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Ren,2011 support certain
experimental MI:0096 pull down in vivo/in vitro Ren,2011 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vitro Ren,2011 support certain InteractionDetection
experimental MI:0424 protein kinase assay in vivo Ren,2011 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P68400) CSK21_HUMAN PF00069 (Pkinase)
Protein kinase domain
39 324 [mitab][xml]
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org