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|Functional site class:||TYR phosphorylation site|
|Functional site description:||Protein tyrosine kinases (PTKs) catalyze the transfer of the gamma-phosphate of ATP to tyrosine residues of protein substrates.|
|Description:||Members of the non-receptor tyrosine kinase Csk family phosphorylate the C-terminal tyrosine residues of the Src family.|
|Pattern:||[TAD][EA].Q(Y)[QE].[GQA][PEDLS] (Probability: 0.0000003)|
|Present in taxons:||Metazoa|
Protein-tyrosine kinases (PTKs) are essential regulators of intracellular signal-transduction pathways in eukaryotes. Tyrosine phosphorylation plays an important role in the control of several cellular processes such as cell proliferation, cell migration, differentiation, immune response, and cell cycle.
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