The Eukaryote Linear Motif resource for Functional Sites in Proteins

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  latest 100 Instances
(click table headers for sorting; Notes column: =Number of Switches, =Number of Interactions)
ELM identifierProtein nameGene nameStartEndSubsequenceLogic#Ev.OrganismNotes
LIG_SUFU_1 CI_DROME ci 255 262 SSAASGSYGHISATALNPMS TP 2 Drosophila melano...
(Fruit fly)
LIG_SUFU_1 GLI2_MOUSE Gli2 268 275 SSAASGSYGHLSAGALSPAF TP 2 Mus musculus
(House mouse)
LIG_SUFU_1 GLI1_HUMAN GLI1 120 127 CTSPGGSYGHLSIGTMSPSL TP 11 Homo sapiens
(Human)
LIG_SUFU_1 GLI3_HUMAN GLI3 333 340 SSSASGSYGHLSASAISPAL TP 1 Homo sapiens
(Human)
LIG_SUFU_1 GLIS3_MOUSE Glis3 348 355 LSPQSEVYGHFLGVRGSCIP TP 3 Mus musculus
(House mouse)
DOC_CKS1_1 SIC1_YEAST SIC1 43 48 KPSQNLVPVTPSTTKSFKNA TP 3 Saccharomyces cer...
DOC_CKS1_1 SIC1_YEAST SIC1 31 36 SSALMQGQKTPQKPSQNLVP TP 3 Saccharomyces cer...
DOC_CKS1_1 SIC1_YEAST SIC1 3 8 MTPSTPPRSRGTRYLAQPSG TP 6 Saccharomyces cer...
DOC_CKS1_1 SWE1_YEAST SWE1 371 376 DNDTDEEISTPTRRKSIIGA TP 1 Saccharomyces cer...
DOC_CKS1_1 SWE1_YEAST SWE1 194 199 YPAKLRIPETPVKKSPLVEG TP 1 Saccharomyces cer...
DOC_CKS1_1 SWE1_YEAST SWE1 119 124 PFHENESVTTPITKRSAEKT TP 1 Saccharomyces cer...
DOC_CKS1_1 CDC6_YEAST CDC6 21 26 RNLFDDAPATPPRPLKRKKL TP 2 Saccharomyces cer...
(Baker"s yeast)
DOC_CKS1_1 CDC6_YEAST CDC6 5 10 MSAIPITPTKRIRRNLFDDA TP 4 Saccharomyces cer...
(Baker"s yeast)
LIG_TRAF2_1 TNR5_HUMAN CD40 104 107 TSETDTICTCEEGWHCTSEA FP 2 Homo sapiens
(Human)
MOD_GSK3_1 CTNB1_HUMAN CTNNB1 30 37 HWQQQSYLDSGIHSGATTTA TP 4 Homo sapiens
(Human)
MOD_GSK3_1 CTNB1_MOUSE Ctnnb1 30 37 HWQQQSYLDSGIHSGATTTA TP 2 Mus musculus
(House mouse)
DOC_PP2B_1 DYN1_HUMAN DNM1 843 849 VPSRPNRAPPGVPRITISDP TP 3 Homo sapiens
(Human)
MOD_GSK3_1 ESR2_HUMAN ESR2 5 12 MDIKNSPSSLNSPSSYNCSQ TP 3 Homo sapiens
(Human)
LIG_SH2_GRB2 ERBB3_HUMAN ERBB3 1262 1265 TTPDEDYEYMNRQRDGGGPG TP 1 Homo sapiens
(Human)
LIG_SH2_SRC DAB1_MOUSE Dab1 198 201 EEDVEDPVYQYIVFEAGHEP TP 5 Mus musculus
(House mouse)
LIG_AP2alpha_2 DAB2_HUMAN DAB2 298 300 PNPDPFRDDPFTQPDQSTPS TP 3 Homo sapiens
(Human)
LIG_AP2alpha_2 DAB2_HUMAN DAB2 293 295 NFFPTPNPDPFRDDPFTQPD TP 3 Homo sapiens
(Human)
LIG_PDZ_Class_1 CLCN3_HUMAN CLCN3 861 866 TDEEREETEEEVYLLNSTTL TP 3 Homo sapiens
(Human)
MOD_CDK_1 CDN1C_MOUSE Cdkn1c 339 345 SPNVAPGVGAVEQTPRKRLR TP 2 Mus musculus
(House mouse)
MOD_CDK_1 CDN1C_HUMAN CDKN1C 307 313 SPSAAPGVGSVEQTPRKRLR TP 2 Homo sapiens
(Human)
MOD_CAAXbox CDC42_RAT Cdc42 188 191 AILAALEPPEPKKSRRCVLL TP 1 Rattus norvegicus
(Norway rat)
MOD_CAAXbox CDC42_HUMAN CDC42 188 191 AILAALEPPEPKKSRRCVLL TP 2 Homo sapiens
(Human)
DEG_SCF_FBW7_1 CCNE1_HUMAN CCNE1 379 384 SPLPSGLLTPPQSGKKQSSG TP 4 Homo sapiens
(Human)
MOD_GSK3_1 CCNE1_HUMAN CCNE1 373 380 EQNRASPLPSGLLTPPQSGK TP 4 Homo sapiens
(Human)
DEG_APCC_KENBOX_2 BUB1B_HUMAN BUB1B 25 29 EGDEWELSKENVQPLRQGRI TP 3 Homo sapiens
(Human)
DEG_APCC_KENBOX_2 BUB1B_HUMAN BUB1B 303 307 IAPPMPRAKENELQAGPWNT TP 2 Homo sapiens
(Human)
DEG_APCC_DBOX_1 CCNB1_HUMAN CCNB1 41 49 KPGLRPRTALGDIGNKVSEQ TP 2 Homo sapiens
(Human)
LIG_IQ CAC1D_RAT Cacna1d 1650 1669 FYATFLIQDYFRKFKKRKEQ TP 1 Rattus norvegicus
(Norway rat)
LIG_SH3_2 SYNJ2_RAT Synj2 1120 1125 VPNRPRPPHPPQRPPPPTGL TP 5 Rattus norvegicus
(Norway rat)
LIG_PDZ_Class_1 PKHG5_MOUSE Plekhg5 1068 1073 QLYRIRTTLLLNSTLTASEV TP 2 Mus musculus
(House mouse)
TRG_ER_diLys_1 S35A2_HUMAN SLC35A2 392 396 RGDLITEPFLPKLLTKVKGS TP 2 Homo sapiens
(Human)
TRG_NLS_MonoExtN_4 SKP2_HUMAN SKP2 67 72 GHPESPPRKRLKSKGSDKDF TP 7 Homo sapiens
(Human)
LIG_TYR_ITIM SIG12_MOUSE Siglec12 430 435 PSSTEEEIHYATLSFHEMKP TP 3 Mus musculus
(House mouse)
TRG_NLS_MonoExtN_4 OGG1_HUMAN OGG1 333 339 SRHAQEPPAKRRKGSKGPEG TP 3 Homo sapiens
(Human)
MOD_CDK_1 ODFP2_HUMAN ODF2 793 799 DGPYSTFLTSSPIRSRSPPA TP 2 Homo sapiens
(Human)
LIG_PDZ_Class_1 GRIK1_RAT Grik1 900 905 SFTSILTCHQRRTQRKETVA TP 4 Rattus norvegicus
(Norway rat)
LIG_SH3_3 TAU_HUMAN MAPT 213 219 GSRSRTPSLPTPPTREPKKV TP 2 Homo sapiens
(Human)
LIG_TYR_ITIM TRML1_HUMAN TREML1 279 284 VLVCSKPVTYATVIFPGGNK TP 2 Homo sapiens
(Human)
LIG_NRBOX TRXR1_HUMAN TXNRD1 46 52 KAYQEGRLQKLLKMNGPEDL TP 3 Homo sapiens
(Human)
TRG_NLS_MonoExtN_4 UNG_HUMAN UNG 15 21 SFFSPSPARKRHAPSPEPAV TP 2 Homo sapiens
(Human)
LIG_14-3-3_1 WWTR1_HUMAN WWTR1 86 91 AGGAQHVRSHSSPASLQLGT TP 4 Homo sapiens
(Human)
LIG_14-3-3_1 YAP1_MOUSE Yap1 109 114 ALTPQHVRAHSSPASLQLGA TP 2 Mus musculus
(House mouse)
LIG_PDZ_Class_1 SYNJ2_RAT Synj2 1288 1293 FVRTVAAQRLTPVDASGSSV TP 9 Rattus norvegicus
(Norway rat)
MOD_GSK3_1 FGD1_HUMAN FGD1 280 287 DGEKVPNRDSGIDSISSPSN TP 1 Homo sapiens
(Human)
LIG_EVH1_1 XIRP1_HUMAN XIRP1 22 26 RMATAEDLPLPPPPALEDLP TP 5 Homo sapiens
(Human)
LIG_EH_1 SYNJ1_HUMAN SYNJ1 1414 1418 SDRTAAPGNPFRAKSEESEA TP 2 Homo sapiens
(Human)
LIG_EH_1 SYNJ1_HUMAN SYNJ1 1403 1407 FITGLTRTNPFSDRTAAPGN TP 2 Homo sapiens
(Human)
LIG_EH_1 SYNJ1_HUMAN SYNJ1 1393 1397 QENMRSSPNPFITGLTRTNP TP 2 Homo sapiens
(Human)
LIG_AP2alpha_2 SYNJ1_HUMAN SYNJ1 1555 1557 PPGTSPPVDPFTTLASKASP TP 2 Homo sapiens
(Human)
LIG_AP2alpha_2 SYNJ1_HUMAN SYNJ1 1323 1325 KRESPLKIDPFEDLSFNLLA TP 2 Homo sapiens
(Human)
LIG_SH2_STAT5 GAB1_HUMAN GAB1 619 622 DSHDSEENYVPMNPNLSSED TP 4 Homo sapiens
(Human)
LIG_SH2_STAT5 GAB1_HUMAN GAB1 472 475 TEPIQEANYVPMTPGTFDFS TP 4 Homo sapiens
(Human)
LIG_SH2_STAT5 GAB1_HUMAN GAB1 447 450 SSEELDENYVPMNPNSPPRQ TP 4 Homo sapiens
(Human)
DOC_WW_Pin1_4 TFCP2_HUMAN TFCP2 288 293 PEITYVNNSPSPGFNSSHSS TP 3 Homo sapiens
(Human)
DOC_WW_Pin1_4 TFCP2_HUMAN TFCP2 286 291 PWPEITYVNNSPSPGFNSSH TP 3 Homo sapiens
(Human)
DOC_WW_Pin1_4 TFCP2_HUMAN TFCP2 306 311 SSFSLGEGNGSPNHQPEPPP TP 3 Homo sapiens
(Human)
DOC_WW_Pin1_4 TFCP2_HUMAN TFCP2 326 331 PVTDNLLPTTTPQEAQQWLH TP 3 Homo sapiens
(Human)
LIG_CaMK_CASK_1 CSKI1_RAT Caskin1 374 379 GPSAPPEEIWVLRKPFAGGD TP 4 Rattus norvegicus
(Norway rat)
LIG_CaMK_CASK_1 APBA1_MOUSE Apba1 381 387 TPDEPKEPIWVMRQDISPTR TP 3 Mus musculus
(House mouse)
LIG_CaMK_CASK_1 APBA1_HUMAN APBA1 376 382 TPDEPKEPIWVMRQDISPTR TP 5 Homo sapiens
(Human)
LIG_CaMK_CASK_1 APBA1_RAT Apba1 378 384 TPDEPKEPIWVMRQDISPTR TP 7 Rattus norvegicus
(Norway rat)
LIG_CaMK_CASK_1 CSKI1_HUMAN CASKIN1 374 379 GPSAPPEEIWVLRKPFAGGD TP 6 Homo sapiens
(Human)
LIG_CaMK_CASK_1 TIAM1_HUMAN TIAM1 1572 1578 LESASEEVIWVRREDFAPSR TP 2 Homo sapiens
(Human)
DOC_WW_Pin1_4 A4_HUMAN APP 668 669 GVVEVDAAVTPEERHLSKMQ TP 4 Homo sapiens
(Human)
DEG_Nend_UBRbox_4 F4IDA7_ARATH HRE1 1 3 MCGGAVISDYIAPEKIARSS TP 3 Arabidopsis thaliana
(Thale cress)
DEG_Nend_UBRbox_4 RAP22_ARATH RAP2-2 1 3 MCGGAIISDFIPPPRSLRVT TP 3 Arabidopsis thaliana
(Thale cress)
DEG_Nend_UBRbox_4 RA212_ARATH RAP2-12 1 3 MCGGAIISDFIPPPRSRRVT TP 9 Arabidopsis thaliana
(Thale cress)
DEG_Nend_UBRbox_4 RAP23_ARATH RAP2-3 1 3 MCGGAIISDYAPLVTKAKGR TP 3 Arabidopsis thaliana
(Thale cress)
DEG_Nend_UBRbox_4 ERF71_ARATH ERF071 1 3 MCGGAIISDFIWSKSESEPS TP 3 Arabidopsis thaliana
(Thale cress)
DEG_Nend_UBRbox_4 RGS16_MOUSE Rgs16 1 3 MCRTLATFPNTCLERAKEFK TP 5 Mus musculus
(House mouse)
DEG_Nend_UBRbox_4 RGS5_MOUSE Rgs5 1 3 MCKGLAALPHSCLERAKEIK TP 8 Mus musculus
(House mouse)
DEG_Nend_UBRbox_4 RGS4_MOUSE Rgs4 1 3 MCKGLAGLPASCLRSAKDMK TP 19 Mus musculus
(House mouse)
DOC_CYCLIN_1 CDN1B_HUMAN CDKN1B 30 33 EHPKPSACRNLFGPVDHEEL TP 5 Homo sapiens
(Human)
DOC_CYCLIN_1 CDN1A_HUMAN CDKN1A 19 22 NPCGSKACRRLFGPVDSEQL TP 4 Homo sapiens
(Human)
DOC_MAPK_1 MP2K1_HUMAN MAP2K1 4 11 MPKKKPTPIQLNPAPDGSAV TP 1 Homo sapiens
(Human)
LIG_PTB_Phospho_1 INSR_HUMAN INSR 993 999 PLGPLYASSNPEYLSASDVF TP 4 Homo sapiens
(Human)
DOC_WD40_RPTOR_TOS_1 4EBP1_HUMAN EIF4EBP1 114 118 RNSPEDKRAGGEESQFEMDI TP 5 Homo sapiens
(Human)
LIG_SH3_2 SOS1_HUMAN SOS1 1151 1156 TDEVPVPPPVPPRRRPESAP TP 4 Homo sapiens
(Human)
LIG_SH2_GRB2 MET_HUMAN MET 1356 1359 HYVHVNATYVNVKCVAPYPS TP 2 Homo sapiens
(Human)
LIG_RGD FINC_HUMAN FN1 1524 1526 ITVYAVTGRGDSPASSKPIS TP 3 Homo sapiens
(Human)
DEG_MDM2_1 P53_HUMAN TP53 19 26 PLSQETFSDLWKLLPENNVL TP 1 Homo sapiens
(Human)
MOD_PKB_1 TSC2_HUMAN TSC2 1457 1465 SPSGLRPRGYTISDSAPSRR TP 1 Homo sapiens
(Human)
MOD_PKB_1 TSC2_HUMAN TSC2 1127 1135 RGARDRVRSMSGGHGLRVGA TP 1 Homo sapiens
(Human)
MOD_PKB_1 TSC2_HUMAN TSC2 976 984 AAEAFRCRSISVSEHVVRSR TP 1 Homo sapiens
(Human)
MOD_PKB_1 TSC2_HUMAN TSC2 934 942 EKDSFRARSTSLNERPKSLR TP 1 Homo sapiens
(Human)
MOD_PKB_1 RAF1_HUMAN RAF1 254 262 GSLSQRQRSTSTPNVHMVST TP 2 Homo sapiens
(Human)
MOD_PKB_1 BRCA1_HUMAN BRCA1 504 512 TNKLKRKRRPTSGLHPEDFI TP 2 Homo sapiens
(Human)
MOD_PKB_1 MDM2_HUMAN MDM2 181 189 SGERQRKRHKSDSISLSFDE TP 2 Homo sapiens
(Human)
MOD_PKB_1 MDM2_HUMAN MDM2 161 169 PSTSSRRRAISETEENSDEL TP 2 Homo sapiens
(Human)
MOD_PKB_1 IKKA_HUMAN CHUK 18 26 GPWEMRERLGTGGFGNVCLY TP 2 Homo sapiens
(Human)
MOD_PKB_1 CASP9_HUMAN CASP9 191 199 DCEKLRRRFSSLHFMVEVKG TP 2 Homo sapiens
(Human)
MOD_PKB_1 NR4A1_HUMAN NR4A1 346 354 SLKGRRGRLPSKPKQPPDAS TP 2 Homo sapiens
(Human)
MOD_GSK3_1 MYC_HUMAN MYC 55 62 IWKKFELLPTPPLSPSRRSG TP 3 Homo sapiens
(Human)
MOD_PKB_1 GSK3B_MOUSE Gsk3b 4 12 MSGRPRTTSFAESCKPVQQP TP 2 Mus musculus
(House mouse)
MOD_PKB_1 FOXO4_HUMAN FOXO4 27 35 FEPQSRPRSCTWPLPRPEIA TP 3 Homo sapiens
(Human)
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DEGHide/Show instances of class type DEG (degradation sites )
DOCHide/Show instances of class type DOC (docking sites)
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Please cite: The Eukaryotic Linear Motif Resource ELM: 10 Years and Counting (PMID:24214962)

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