The Eukaryote Linear Motif resource for Functional Sites in Proteins

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ELM identifierSequenceStartEndSubsequenceInstance Logic#EvidencePDBOrganism
LIG_eIF4E_2 DDX3X_HUMAN 38 44 TASKGRYIPPHLRNREATKG true positive 1 --- Homo sapiens (Human)
LIG_eIF4E_1 IF4G_SCHPO 830 836 KAGKYEYDVPFLLQFQSVYT true positive 1 --- Schizosaccharomyces pombe 972h-
LIG_eIF4E_1 CUP_DROME 327 333 SKPVKSYTRSRLMDIRNGMF true positive 1 --- Drosophila melanogaster (Fruit fly)
LIG_eIF4E_1 GEMI5_HUMAN 992 998 LSIHKVYEAVELLKSNHFYR true positive 1 --- Homo sapiens (Human)
LIG_eIF4E_1 4EBP3_HUMAN 40 46 GGTRIIYDRKFLLECKNSPI true positive 1 --- Homo sapiens (Human)
LIG_eIF4E_1 IF41_WHEAT 66 72 SRERVRYSRDQLLDLRKITD true positive 1 --- Triticum aestivum (Bread wheat)
LIG_eIF4E_1 4EBP2_HUMAN 54 60 GGTRIIYDRKFLLDRRNSPM true positive 1 --- Homo sapiens (Human)
LIG_eIF4E_1 4EBP1_HUMAN 54 60 GGTRIIYDRKFLMECRNSPV true positive 2 --- Homo sapiens (Human)
LIG_eIF4E_1 CAF20_YEAST 4 10 MIKYTIDELFQLKPSLTLEV true positive 1 --- Saccharomyces cerevisiae S288c
LIG_eIF4E_1 O61380_DROME 621 627 PSGKKQYDREQLLQLREVKA true positive 1 --- Drosophila melanogaster (Fruit fly)
LIG_eIF4E_1 IF4F2_YEAST 423 429 PSVKYTYGPTFLLQFKDKLK true positive 1 --- Saccharomyces cerevisiae S288c
LIG_eIF4E_1 IF4F1_YEAST 452 458 EHVKYTYGPTFLLQFKDKLN true positive 1 --- Saccharomyces cerevisiae S288c
LIG_eIF4E_1 IF4G3_HUMAN 624 630 TEGKKQYDREFLLDFQFMPA true positive 1 --- Homo sapiens (Human)
LIG_eIF4E_1 IF4G1_HUMAN 612 618 LEEKKRYDREFLLGFQFIFA true positive 2 --- Homo sapiens (Human)
TRG_ER_diArg_1 HMDH_NICSY 3 6 MDVRRRSEKPAYPTKEFAAG true positive 1 --- Nicotiana sylvestris (Wood tobacco)
TRG_ER_diArg_1 S12A5_RAT 1101 1104 VLLNMPGPPRNRNGDENYME true positive 2 --- Rattus norvegicus (Norway rat)
TRG_ER_diArg_1 SIAT9_MOUSE 11 13 TEAVGGAARRPQKLRSQAAA true positive 5 --- Mus musculus (House mouse)
TRG_ER_diArg_1 CFTR_HUMAN 553 556 GITLSGGQRARISLARAVYK false positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 P2RX7_HUMAN 575 578 ANLPSCCRWRIRKEFPKSEG true positive 2 --- Homo sapiens (Human)
TRG_ER_diArg_1 C8ZIX9_YEAS8 8 11 MSLSLVSYRLRKNPWVNIFL true positive 4 --- Saccharomyces cerevisiae EC1118
TRG_ER_diArg_1 MSHR_HUMAN 160 163 YHSIVTLPRARRAVAAIWVA true positive 4 --- Homo sapiens (Human)
TRG_ER_diArg_1 SOAT1_HUMAN 10 13 VGEEKMSLRNRLSKSRENPE true positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 SRPRB_HUMAN 7 9 MASADSRRVADGGGAGGTFQ true positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 SGMR1_HUMAN 7 9 MQWAVGRRWAWAALLLAVAA true positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 PPLA_HUMAN 12 14 VQYLTRSAIRRASTIEMPQQ true positive 5 --- Homo sapiens (Human)
TRG_ER_diArg_1 ADA10_HUMAN 723 725 PLPGTLKRRRPPQPIQQPQR true positive 4 --- Homo sapiens (Human)
TRG_ER_diArg_1 GPAA1_HUMAN 9 11 MGLLSDPVRRRALARLVLRL true negative 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 GRIK5_HUMAN 862 865 SCRKTSRSRRRRRPGGPSRA true positive 5 --- Homo sapiens (Human)
TRG_ER_diArg_1 V2R_HUMAN 247 249 GPSERPGGRRRGRRTGSPGE true positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 GABR1_HUMAN 923 926 QLQSRQQLRSRRHPPTPPEP true positive 3 --- Homo sapiens (Human)
TRG_ER_diArg_1 PAR4_HUMAN 182 185 RYLALVHPLRARALRGRRLA true positive 4 --- Homo sapiens (Human)
TRG_ER_diArg_1 HG2A_HUMAN 3 5 MHRRRSRSCREDQKPVMDDQ true positive 4 --- Homo sapiens (Human)
TRG_ER_diArg_1 GPR15_HUMAN 352 354 LSTFIHAEDFARRRKRSVSL true positive 6 --- Homo sapiens (Human)
TRG_ER_diArg_1 ADA22_HUMAN 851 854 KKKIRGKRFRPRSNSTETLS true positive 4 --- Homo sapiens (Human)
TRG_ER_diArg_1 Q58F09_HUMAN 7 9 MARGERRRRAVPAEGVRTAE true positive 2 --- Homo sapiens (Human)
TRG_ER_diArg_1 SCNAA_RAT 495 497 SFLGLSSGRRRASHGSVFHF true positive 4 --- Rattus norvegicus (Norway rat)
TRG_ER_diArg_1 IRK11_HUMAN 368 371 TLASARGPLRKRSVPMAKAK true positive 9 --- Homo sapiens (Human)
TRG_ER_diArg_1 IRK8_HUMAN 380 383 SELSHQNSLRKRNSMRRNNS true positive 5 --- Homo sapiens (Human)
TRG_ER_diArg_1 ABCC8_HUMAN 648 651 AVPLRVVNRKRPAREDCRGL true positive 5 --- Homo sapiens (Human)
TRG_ER_diArg_1 NMDZ1_HUMAN 893 895 STLASSFKRRRSSKDTSTGG true positive 5 --- Homo sapiens (Human)
LIG_OCRL_FandH_1 DP13A_HUMAN 403 415 PSPSFQQRHESLRPAAGQSR true positive 22 2EJ8 Homo sapiens (Human)
LIG_OCRL_FandH_1 SESQ2_HUMAN 223 235 ETSCFSTLHDWYGQEIVELR true positive 22 --- Homo sapiens (Human)
LIG_OCRL_FandH_1 SESQ1_HUMAN 223 235 DMAPFARLHECYGQEIRALR true positive 27 3QIS Homo sapiens (Human)
LIG_TNKBM_1 TB182_HUMAN 1507 1514 RDSPPSWRPQPDGEASQTED true positive 1 --- Homo sapiens (Human)
LIG_TNKBM_1 CASC3_HUMAN 145 152 KSTVTGERQSGDGQESTEPV true positive 2 --- Homo sapiens (Human)
LIG_TNKBM_1 AXIN1_HUMAN 21 28 SFTEDAPRPPVPGEEGELVS true positive 4 --- Homo sapiens (Human)
LIG_TNKBM_1 MCL1_HUMAN 77 84 PDSRRVARPPPIGAEVPDVT true positive 1 3TWU Homo sapiens (Human)
LIG_TNKBM_1 FNBP1_HUMAN 514 521 VNNCAQDRESPDGSYTEEQS true positive 4 3TWX Homo sapiens (Human)
LIG_TNKBM_1 LCAP_HUMAN 95 102 RNSATGYRQSPDGACSVPSA true positive 3 3TWW Homo sapiens (Human)
LIG_TNKBM_1 NUMA1_HUMAN 1742 1749 SITSKLPRTQPDGTSVPGEP true positive 2 3TWV Homo sapiens (Human)
LIG_TNKBM_1 TERF1_HUMAN 12 19 SSAAPSPRGCADGRDADPTE true positive 3 3TWS Homo sapiens (Human)
LIG_TNKBM_1 BABA1_HUMAN 47 54 AQASVGSRSEGEGEAASADD true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 BABA1_HUMAN 27 34 AEPRPRTRSNPEGAEDRAVG true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 A9UF02_HUMAN 115 122 PAEEPEARPDGEGSPGKARP true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 RAD54_HUMAN 690 697 CVNSRQIRPPPDGSDCTSDL true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 FAT4_HUMAN 4826 4833 RRPLSRTRNPADGIPAPESS true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 FAT4_HUMAN 4571 4578 YGDDMTVRKQPEGNPKPDII true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 STRN_HUMAN 301 308 EEGDNESRSAGDGTDWEKED true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 DISC1_HUMAN 222 229 SLGSAGERGEAEGCPPSREA true positive 3 --- Homo sapiens (Human)
LIG_TNKBM_1 3BP2_HUMAN 414 421 PQLPHLQRSPPDGQSFRSFS true positive 4 --- Homo sapiens (Human)
LIG_14-3-3_3 ADA22_HUMAN 831 836 ICENGRPRSNSWQGNLGGNK true positive 2 --- Homo sapiens (Human)
LIG_14-3-3_3 ITB2_HUMAN 755 760 NNDNPLFKSATTTVMNPKFA true positive 4 --- Homo sapiens (Human)
MOD_TYR_ITAM CD3Z_HUMAN 69 86 QNQLYNELNLGRREEYDVLD true positive 3 --- Homo sapiens (Human)
MOD_TYR_ITAM CD3E_HUMAN 185 202 PNPDYEPIRKGQRDLYSGLN true positive 5 1A81 Homo sapiens (Human)
LIG_14-3-3_3 PTN3_HUMAN 832 837 VNYVRSLRVDSEPVLVHCSA true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 PTN3_HUMAN 356 361 VWNPAMRRSLSVEHLETKSL true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 RIM15_YEAST 1072 1077 FSLLDISRSSTPPLANPTNS true positive 1 --- Saccharomyces cerevisiae (Baker's yeast)
LIG_14-3-3_3 HDAC4_HUMAN 629 634 GGHRPLSRAQSSPASATFPV true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 FOXO3_HUMAN 250 255 SGKAPRRRAVSMDNSNKYTK true positive 0 --- Homo sapiens (Human)
LIG_14-3-3_3 FOXO3_HUMAN 29 34 FEPQSRPRSCTWPLQRPELQ true positive 0 --- Homo sapiens (Human)
LIG_14-3-3_3 IRS1_HUMAN 267 272 MSDEFRPRSKSQSSSNCSNP true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 IRS1_HUMAN 638 643 DYMPMSPKSVSAPQQIINPI true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 IRS1_HUMAN 371 376 RLHPPLNHSRSIPMPASRCS true positive 1 --- Homo sapiens (Human)
LIG_14-3-3_3 SLOB_DROME 76 81 RQIYSSNRSASSEQDNSDLS true positive 1 --- Drosophila melanogaster (Fruit fly)
LIG_14-3-3_3 SLOB_DROME 51 56 HKANGLKRSNSAIEFDVSAL true positive 1 --- Drosophila melanogaster (Fruit fly)
LIG_14-3-3_3 KSR1_MOUSE 389 394 LPLARLRRTESVPSDINNPV true positive 1 --- Mus musculus (House mouse)
LIG_14-3-3_3 KSR1_MOUSE 294 299 PSFPTLTRSKSHESQLGNRI true positive 1 --- Mus musculus (House mouse)
LIG_14-3-3_1 MPIP3_HUMAN 213 218 VSRSGLYRSPSMPENLNRPR true positive 1 --- Homo sapiens (Human)
TRG_LysEnd_APsAcLL_1 CD4_HUMAN 434 439 RQAERMSQIKRLLSEKKTCQ true positive 6 --- Homo sapiens (Human)
LIG_PP1 RB_HUMAN 872 878 SNPPKPLKKLRFDIEGSDEA true positive 4 3N5U Homo sapiens (Human)
LIG_PDZ_Class_1 SYGP1_RAT 1303 1308 KRLLDAQRGSFPPWVQQTRV true positive 4 --- Rattus norvegicus (Norway rat)
LIG_PDZ_Class_2 NRX3A_RAT 1573 1578 QASSKSGHKKQKNKDKEYYV true positive 1 --- Rattus norvegicus (Norway rat)
LIG_WW_Pin1_4 CEP55_MOUSE 420 425 REPESRVKATSPKSPSAALN true positive 3 --- Mus musculus (House mouse)
LIG_WW_Pin1_4 X_HBVA3 38 43 SGPLGTLSSPSPSAVPADHG true positive 2 --- Hepatitis B virus adw2/Rutter/1979
LIG_WW_Pin1_4 BTG2_HUMAN 144 149 CKNQVLLGRSSPSKNYVMAV true positive 3 --- Homo sapiens (Human)
LIG_WW_Pin1_4 FAK1_HUMAN 907 912 EGVKLQPQEISPPPTANLDR true positive 4 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NOTC1_HUMAN 2133 2138 GAPLGGTPTLSPPLCSPNGY true positive 5 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NOTC1_HUMAN 2129 2134 PQLHGAPLGGTPTLSPPLCS true positive 5 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NOTC1_HUMAN 2118 2123 RLLDEYNLVRSPQLHGAPLG true positive 5 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NEK6_HUMAN 242 247 CLLYEMAALQSPFYGDKMNL true positive 2 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NEK6_HUMAN 212 217 HSLVGTPYYMSPERIHENGY true positive 2 --- Homo sapiens (Human)
LIG_WW_Pin1_4 FBX5A_XENLA 7 12 MMCGFASNQSPKKLSSKKSS true positive 2 --- Xenopus laevis (African clawed frog)
LIG_WW_Pin1_4 B2L11_MOUSE 62 67 SPQGPLAPPASPGPFATRSP true positive 4 --- Mus musculus (House mouse)
LIG_WW_Pin1_4 GEPH_MOUSE 197 202 PPPLSPPPTTSPHKQTEDKG true positive 4 --- Mus musculus (House mouse)
LIG_WW_Pin1_4 GEPH_MOUSE 191 196 EDLPSPPPPLSPPPTTSPHK true positive 4 --- Mus musculus (House mouse)
LIG_WW_Pin1_4 GEPH_MOUSE 185 190 EVHDELEDLPSPPPPLSPPP true positive 4 --- Mus musculus (House mouse)
LIG_WW_Pin1_4 WEE1B_XENLA 183 188 STPQVNINPFTPDSLEIQSS true positive 3 --- Xenopus laevis (African clawed frog)
LIG_WW_Pin1_4 STAT3_HUMAN 724 729 TCSNTIDLPMSPRTLDSLMQ true positive 3 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NR4A1_HUMAN 137 142 DYYGSPCSAPSPSTPSFQPP true positive 1 --- Homo sapiens (Human)
LIG_WW_Pin1_4 NR4A1_HUMAN 92 97 ASSTSSSSATSPASASFKFE true positive 1 --- Homo sapiens (Human)
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LIGHide/Show instances of class type LIG (ligand binding sites)
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Please cite: ELM - the database of eukaryotic linear motifs (PMID:22110040)
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