| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004906 | P12931 SRC SRC_HUMAN |
530 | 534 | AFLEDYFTSTEPQYQPGENL | TP |
1FMK 2SRC |
Homo sapiens (Human) | 536 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0114 | x-ray crystallography | in vitro | Xu,1997 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0033 | deletion analysis | Gilmer,1994 | support | certain | FeatureDetection | |
| experimental | MI:0411 | elisa | in vitro | Gilmer,1994 | support | certain | InteractionDetection ParticipantIdentification |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Bradshaw,1998 | support | certain | InteractionDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Xu,1999 | support | certain | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P12931) SRC_HUMAN | IPR000980
(SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps |
149 | 248 | [mitab][xml] | |
| (P00524) SRC_RSVSA | IPR000980
(SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps |
146 | 245 | 29.4/29.4 | [mitab][xml] |
Pathways
- Adherens junction
- Axon guidance
- Bacterial invasion of epithelial cells
- Bladder cancer
- C type lectin receptor signaling pathway
- Chemical carcinogenesis reactive oxygen species
- Chemical carcinogenesis receptor activation
- Chemokine signaling pathway
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endocytosis
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Estrogen signaling pathway
- Fluid shear stress and atherosclerosis
- Focal adhesion
- GABAergic synapse
- Gap junction
- GnRH signaling pathway
- Hepatitis B
- Herpes simplex virus 1 infection
- Human cytomegalovirus infection
- Inflammatory mediator regulation of TRP channels
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- Mitophagy animal
- Neutrophil extracellular trap formation
- Oxytocin signaling pathway
- Pathogenic Escherichia coli infection
- Platelet activation
- Prolactin signaling pathway
- Proteoglycans in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- Relaxin signaling pathway
- Shigellosis
- Thyroid hormone signaling pathway
- Tight junction
- Tuberculosis
- VEGF signaling pathway
- Viral carcinogenesis
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement