| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004904 | P15498 VAV1 VAV_HUMAN |
158 | 167 | VEEDEDLYDCVENEEAEGDE | TP | --- | Homo sapiens (Human) | 845 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | Miletic,2006 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06239) LCK_HUMAN | IPR000980
(SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps |
125 | 224 | [mitab][xml] |
Pathways
- B cell receptor signaling pathway
- Chemokine signaling pathway
- Fc epsilon RI signaling pathway
- Fc gamma R mediated phagocytosis
- Focal adhesion
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- Natural killer cell mediated cytotoxicity
- Proteoglycans in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- T cell receptor signaling pathway
- Yersinia infection
- cAMP signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement