The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004904 P15498 VAV1
158 167 VEEDEDLYDCVENEEAEGDE TP --- Homo sapiens (Human) 845

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro Miletic,2006 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06239) LCK_HUMAN IPR000980 (SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps
125 224 [mitab][xml]

o  Pathways

KEGG: The sequence P15498 is implicated in the following 14 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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