Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004918 | P02751 FN1 FINC_HUMAN |
1615 | 1619 | YVVSVYAQNPSGESQPLVQT | TP |
4MMX |
Homo sapiens (Human) | 2386 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:1088 | phenotype-based detection assay | Chen,1996 | support | certain | InteractionDetection | |
experimental | MI:0411 | elisa | in vitro | Ozawa,2016 | support | certain | InteractionDetection ParticipantIdentification |
experimental | MI:0411 | elisa | in vitro | Jovanovic,2007 | support | certain | InteractionDetection ParticipantIdentification |
experimental | MI:0107 | surface plasmon resonance | in vitro | Jovanovic,2007 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Van Agthoven,2014 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P08648) ITA5_HUMAN | PF01839
(FG-GAP)
FG-GAP repeat |
326 | 368 | 0.0108/0.0108 | [mitab][xml] |
(P06756) ITAV_HUMAN | PF01839
(FG-GAP)
FG-GAP repeat |
252 | 286 | 0.18/0.18 | [mitab][xml] |
(P05556) ITB1_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
138 | 382 | 0.0108/0.0108 | [mitab][xml] |
(P05106) ITB3_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
133 | 381 | [mitab][xml] | |
(P18084) ITB5_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
133 | 382 | [mitab][xml] | |
(P18564) ITB6_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
128 | 375 | 0.18/0.18 | [mitab][xml] |
(P26012) ITB8_HUMAN | PF00362
(Integrin_beta)
Integrin, beta chain |
142 | 388 | [mitab][xml] |
Pathways
KEGG: The sequence P02751 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Amoebiasis
- Bacterial invasion of epithelial cells
- ECM receptor interaction
- Focal adhesion
- Human papillomavirus infection
- PI3K Akt signaling pathway
- Pathways in cancer
- Proteoglycans in cancer
- Regulation of actin cytoskeleton
- Small cell lung cancer
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement