The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003134 Q9Y6B2 EID1
EID1_HUMAN
175 187 LMVVNRLTEELGCDEIIDRE TP 7SMD  
Homo sapiens (Human) 187

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Putta,2022 support certain InteractionDetection FeatureDetection
experimental MI:0119 mutation decreasing interaction in vivo/in vitro Putta,2022 support certain InteractionDetection
experimental MI:0573 mutation disrupting interaction in vivo/in vitro Putta,2022 support certain
experimental MI:0905 amplified luminescent proximity homogeneous assay Putta,2022 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Putta,2022 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro MacLellan,2000 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Miyake,2000 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Miyake,2000 support certain FeatureDetection
experimental MI:0018 two hybrid in vivo MacLellan,2000 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro MacLellan,2000 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 6.6/6.6 [mitab][xml]
(P28749) RBL1_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
787 943 7.7/7.7 [mitab][xml]
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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