The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003149 P42753 CYCD3-1
20 38 DALYCEEEKWDDEGEEVEEN TP --- Arabidopsis thaliana (Thale cress) 376

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0905 amplified luminescent proximity homogeneous assay Putta,2022 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Dunaief,1994 support certain
predicted MI:0101 sequence based prediction in silico Soni,1995 support likely InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Dunaief,1994 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 0.4/0.4 [mitab][xml]
(P28749) RBL1_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
787 943 0.9/0.9 [mitab][xml]

o  Pathways

KEGG: The sequence P42753 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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