| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003141 | Q13547 HDAC1 HDAC1_HUMAN |
411 | 428 | SDKRIACEEEFSDSEEEGEG | TP |
7SME |
Homo sapiens (Human) | 482 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0114 | x-ray crystallography | in vitro | Putta,2022 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0007 | anti tag coimmunoprecipitation | in vivo | Putta,2022 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Putta,2022 | support | certain | FeatureDetection |
| experimental | MI:0905 | amplified luminescent proximity homogeneous assay | Putta,2022 | support | certain | InteractionDetection | |
| experimental | MI:0096 | pull down | in vivo/in vitro | support | certain | InteractionDetection | |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Vortmeyer,1999 | support | certain | |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Singh,2005 | support | certain | InteractionDetection |
| experimental | MI:0405 | competition binding | in vitro | Vortmeyer,1999 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Vortmeyer,1999 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Ferreira,1998 | support | certain | FeatureDetection |
| experimental | MI:0405 | competition binding | in vitro | Ferreira,1998 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Ferreira,1998 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Luo,1998 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Magnaghi-Jaulin,1998 | support | certain | FeatureDetection |
| experimental | MI:0405 | competition binding | in vitro | Magnaghi-Jaulin,1998 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Magnaghi-Jaulin,1998 | support | certain | InteractionDetection |
| experimental | MI:0405 | competition binding | in vitro | Brehm,1998 | support | certain | InteractionDetection |
| experimental | MI:0018 | two hybrid | in vivo | Brehm,1998 | contradict | likely | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Brehm,1998 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06400) RB_HUMAN | PF01857
(RB_B)
Retinoblastoma-associated protein B domain |
646 | 765 | 10.0/10.0 | [mitab][xml] |
| (P28749) RBL1_HUMAN | IPR002719
(Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno... |
787 | 943 | 80.0/80.0 | [mitab][xml] |
Pathways
- Alcoholism
- Amphetamine addiction
- Cell cycle
- Chronic myeloid leukemia
- Epstein Barr virus infection
- Human papillomavirus infection
- Huntington disease
- Longevity regulating pathway multiple species
- MicroRNAs in cancer
- Neutrophil extracellular trap formation
- Notch signaling pathway
- Pathways in cancer
- Thyroid hormone signaling pathway
- Transcriptional misregulation in cancer
- Viral carcinogenesis
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement