| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004908 | P06239 LCK LCK_HUMAN |
505 | 509 | LRSVLEDFFTATEGQYQPQP | TP |
1LCK |
Homo sapiens (Human) | 509 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0114 | x-ray crystallography | in vitro | Eck,1994 | support | certain | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06239) LCK_HUMAN | IPR000980
(SH2 domain)
The Src homology 2 (SH2) domain is a protein domain of about 100 amino-acid residues first identified as a conserved sequence region between the oncoproteins Src and Fps |
125 | 224 | [mitab][xml] |
Pathways
- Human T cell leukemia virus 1 infection
- NF kappa B signaling pathway
- Natural killer cell mediated cytotoxicity
- Osteoclast differentiation
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Primary immunodeficiency
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Yersinia infection
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement