The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003126 Q13029 PRDM2
PRDM2_HUMAN
309 328 EIRCDEKPEDLLEEPKTTSE TP --- Homo sapiens (Human) 1718

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0905 amplified luminescent proximity homogeneous assay Putta,2022 support certain InteractionDetection
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Buyse,1995 support certain
experimental MI:0053 fluorescence polarization spectroscopy in vitro Sun,2015 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Sun,2015 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Sun,2015 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Sun,2015 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Buyse,1997 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Buyse,1997 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Buyse,1995 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
646 765 0.64/0.64 [mitab][xml]
(P28749) RBL1_HUMAN IPR002719 (Retinoblastoma-associated protein, B-box)
This entry includes retinoblastoma-associated protein (RB, also known as pRb, RB, p1051), retinoblastoma-like protein 1 (RBL1, also known as p107) and retinoblastoma-like protein 2 (RBL2, also kno...
787 943 21.0/21.0 [mitab][xml]

o  Pathways

KEGG: The sequence Q13029 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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