- ELM database update
Several new ELM classes and instances have been added:
These ELM classes have been updated:
- ELM classes 14-3-3 have been merged
Some of the oldest entries in the database have been updated. They had been proven to be difficult and it took quite an effort to sort these out. Finally, we can announce that the classes
LIG_14-3-3_1 and LIG_14-3-3_2
have been merged into LIG_14-3-3_CanoR_1,
LIG_14-3-3_3 has been dropped,
and a C-terminal class has been added: LIG_14-3-3_CterR_2
Featured paper:"Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation."
Download a movie about a molecular switch involved in the formation of the ALG2/Alix complex
Functional site prediction
Short patterns applied to proteins are usually not statistically significant: Therefore we can't provide E-values as with BLAST searches. This means that most matches shown are more likely to be false positives than true matches. We hope that ELM server results will prove useful as guides to experimentation but they should not be treated as factual findings.
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement