The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003917 Q9Y253 POLH
POLH_HUMAN
701 710 KRPRPEGMQTLESFFKPLTH TP 2VZK  
Homo sapiens (Human) 713

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Hishiki,2009 support likely FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Hishiki,2009 support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Hishiki,2009 support likely
experimental MI:0107 surface plasmon resonance in vitro Hishiki,2009 support likely InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Hishiki,2009 support likely InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 0.4/0.4 [mitab][xml]

o  Pathways

KEGG: The sequence Q9Y253 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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