ELM - instance LIG_PCNA_PIPBox_1 in sequence Q9Y253 at position 701

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI003917	Q9Y253 POLH POLH_HUMAN	701	710	KRPRPEGMQTLESFFKPLTH	TP	2VZK	Homo sapiens (Human)	713

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0074	mutation analysis	in vivo/in vitro	Hishiki,2009	support	likely	FeatureDetection
experimental	MI:0096	pull down	in vivo/in vitro	Hishiki,2009	support	likely	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Hishiki,2009	support	likely
experimental	MI:0107	surface plasmon resonance	in vitro	Hishiki,2009	support	likely	InteractionDetection FeatureDetection
experimental	MI:0114	x-ray crystallography	in vitro	Hishiki,2009	support	likely	InteractionDetection FeatureDetection

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P12004) PCNA_HUMAN	PF02747 (PCNA_C) Proliferating cell nuclear antigen, C-terminal domain	127	254	0.4/0.4	[mitab][xml]

Pathways

KEGG: The sequence Q9Y253 is implicated in the following 2 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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