The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002044 P78314 SH3BP2
3BP2_HUMAN
414 421 PQLPHLQRSPPDGQSFRSFS TP --- Homo sapiens (Human) 561

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Guettler,2011 support certain
experimental MI:0053 fluorescence polarization spectroscopy in vitro Guettler,2011 support certain InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Guettler,2011 support certain FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Guettler,2011 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9H2K2) TNKS2_HUMAN PF00023 (Ank)
Ankyrin repeat
525 557 [mitab][xml]

o  Pathways

The sequence P78314 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)

o  Diseases

Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org