The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003920 P18858 LIG1
DNLI1_HUMAN
2 11 MQRSIMSFFHPKKEGKAKKP TP --- Homo sapiens (Human) 919

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0367 green fluorescent protein tag in vivo Montecucco,1998 support certain
experimental MI:0403 colocalization in vitro Montecucco,1998 support certain
experimental MI:0074 mutation analysis in vivo/in vitro Montecucco,1998 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Montecucco,1998 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Montecucco,1998 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Montecucco,1998 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Wilson,2017 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 7.2/7.2 [mitab][xml]

o  Pathways

KEGG: The sequence P18858 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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