The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001875 Q14524 SCN5A
SCN5A_HUMAN
1902 1921 EVSAMVIQRAFRRHLLQRSL TP 2L53  
Homo sapiens (Human) 2016

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0051 fluorescence technology Shah,2006 support certain InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Shah,2006 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Shah,2006 support certain FeatureDetection
experimental MI:0077 nuclear magnetic resonance in vitro Chagot,2011 support certain InteractionDetection FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Chagot,2011 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62158) CALM_HUMAN PF13499 (EF_hand_7)
EF-hand domain pair
8 73 [mitab][xml]
(P62158) CALM_HUMAN PF13499 (EF_hand_7)
EF-hand domain pair
85 146 [mitab][xml]

o  Pathways

KEGG: The sequence Q14524 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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