Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI001868 | Q13936 CACNA1C CAC1C_HUMAN |
1666 | 1685 | FYATFLIQEYFRKFKKRKEQ | TP |
2F3Y |
Homo sapiens (Human) | 2221 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Fallon,2005 | support | certain | FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Fallon,2005 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P62158) CALM_HUMAN | PF13499
(EF_hand_7)
EF-hand domain pair |
8 | 73 | [mitab][xml] | |
(P62158) CALM_HUMAN | PF13499
(EF_hand_7)
EF-hand domain pair |
85 | 146 | [mitab][xml] |
Pathways
KEGG: The sequence Q13936 is implicated in the following 34 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Adrenergic signaling in cardiomyocytes
- Aldosterone synthesis and secretion
- Alzheimer disease
- Amphetamine addiction
- Arrhythmogenic right ventricular cardiomyopathy
- Calcium signaling pathway
- Cardiac muscle contraction
- Chemical carcinogenesis receptor activation
- Cholinergic synapse
- Circadian entrainment
- Cortisol synthesis and secretion
- Cushing syndrome
- Dilated cardiomyopathy
- Dopaminergic synapse
- GABAergic synapse
- Glutamatergic synapse
- GnRH secretion
- GnRH signaling pathway
- Growth hormone synthesis, secretion and action
- Hypertrophic cardiomyopathy
- Insulin secretion
- Long term potentiation
- MAPK signaling pathway
- Oxytocin signaling pathway
- Pathways of neurodegeneration multiple diseases
- Prion disease
- Renin secretion
- Retrograde endocannabinoid signaling
- Serotonergic synapse
- Taste transduction
- Type II diabetes mellitus
- Vascular smooth muscle contraction
- cAMP signaling pathway
- cGMP PKG signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement