ELM - instance TRG_ENDOCYTIC_2 in sequence Q9J3M8 at position 582

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI001842	Q9J3M8 gE GE_VZVO	582	585	SPYNQSMYYAGLPVDDFEDS	TP	---	Human herpesvirus 3 strain Oka vaccine	623

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0101	sequence based prediction	in silico	Alconada,1999	support	certain	InteractionDetection
experimental	MI:0017	classical fluorescence spectroscopy	in vitro	Alconada,1996	support	certain	InteractionDetection
experimental	MI:0074	mutation analysis	in vivo/in vitro	Alconada,1996	support	certain	FeatureDetection
experimental	MI:0005	alanine scanning	in vivo/in vitro/in silico	Alconada,1996	support	certain	FeatureDetection

Switches

This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

SWTI000232:

Binding of 18348" target="_blank">1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to the AP-2 complex alpha, beta and mu subunits exposes a binding site on the AP-2 complex subunit mu (AP2M1) subunit for recruitment of Envelope glycoprotein E (gE) via an endocytosis motif.

Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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