ELM - instance LIG_PCNA_PIPBox_1 in sequence P26358 at position 164

Instance

Accession	Acc. Gene-, Name	Start	End	Subsequence	Logic	PDB	Organism	Length
ELMI000797	P26358 DNMT1 DNMT1_HUMAN	164	173	RKSTRQTTITSHFAKGPAKR	TP	6K3A	Homo sapiens (Human)	1616

Instance evidence

Evidence class	PSI-MI	Method	BioSource	PubMed	Logic	Reliability	Notes
experimental	MI:0107	surface plasmon resonance	in vitro	Wilson,2017	support	certain	InteractionDetection FeatureDetection
experimental	MI:0096	pull down	in vivo/in vitro	Wilson,2017	support	certain	InteractionDetection
experimental	MI:0519	glutathione s tranferase tag	in vitro	Wilson,2017	support	certain
experimental	MI:0405	competition binding	in vitro	Chuang,1997	support	certain	InteractionDetection
experimental	MI:0053	fluorescence polarization spectroscopy	in vitro	Chuang,1997	support	certain	InteractionDetection
experimental	MI:0040	electron microscopy	in vivo/in vitro	Chuang,1997	support	certain	InteractionDetection
experimental	MI:0077	nuclear magnetic resonance	in vitro	Chuang,1997	support	certain	InteractionDetection FeatureDetection
experimental	MI:0065	isothermal titration calorimetry	in vitro	Jimenji,2019	support	certain	InteractionDetection
experimental	MI:0114	x-ray crystallography	in vitro	Jimenji,2019	support	certain	InteractionDetection FeatureDetection
not annotated		not specified		Chuang,1997	not specified	not specified

Interactions

Uniprot Id	Domain family	Domain Start	Domain End	Affinity Min/Max (µMol)	Notes
(P12004) PCNA_HUMAN	PF02747 (PCNA_C) Proliferating cell nuclear antigen, C-terminal domain	127	254	4.7/4.7	[mitab][xml]

Pathways

KEGG: The sequence P26358 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)

Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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