The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002595 Q13309 SKP2
SKP2_HUMAN
67 72 GHPESPPRKRLKSKGSDKDF TP --- Homo sapiens (Human) 424

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Gao,2009 support certain
experimental MI:0416 fluorescence microscopy Gao,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Gao,2009 support certain FeatureDetection
experimental MI:0416 fluorescence microscopy Inuzuka,2012 support certain InteractionDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Inuzuka,2012 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Inuzuka,2012 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Inuzuka,2012 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O15131) IMA6_HUMAN PF00514 (Arm)
Armadillo/beta-catenin-like repeat
[mitab][xml]
(O60684) IMA7_HUMAN PF00514 (Arm)
Armadillo/beta-catenin-like repeat
[mitab][xml]

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence Q13309 is implicated in the following 8 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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