The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003815 P25054 APC
APC_HUMAN
1507 1513 SCSSSLSALSLDEPFIQKDV TP --- Homo sapiens (Human) 2843

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Ferrarese,2007 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vivo Ferrarese,2007 support certain InteractionDetection
experimental MI:0039 edman degradation in vitro Ferrarese,2007 support certain ParticipantIdentification

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P48729) KC1A_HUMAN PF00069 (Pkinase)
Protein kinase domain
17 259 [mitab][xml]
(P48730) KC1D_HUMAN PF00069 (Pkinase)
Protein kinase domain
9 267 [mitab][xml]
(Q9HCP0) KC1G1_HUMAN PF00069 (Pkinase)
Protein kinase domain
44 303 [mitab][xml]

o  Pathways

KEGG: The sequence P25054 is implicated in the following 10 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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