The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003207 Q14790 CASP8
CASP8_HUMAN
384 391 QPYLEMDLSSPQTRYIPDEA TP --- Homo sapiens (Human) 479

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Matthess,2010 support certain
experimental MI:0424 protein kinase assay in vivo Matthess,2010 support certain InteractionDetection
experimental MI:0113 western blot in vitro Matthess,2010 support certain ParticipantIdentification FeatureDetection
experimental MI:1297 phosphoamino acid analysis Matthess,2010 support certain FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Matthess,2010 support certain FeatureDetection
experimental MI:0424 protein kinase assay in vitro Matthess,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06493) CDK1_HUMAN PF00069 (Pkinase)
Protein kinase domain
4 287 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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