| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI003207 | Q14790 CASP8 CASP8_HUMAN |
384 | 391 | QPYLEMDLSSPQTRYIPDEA | TP | --- | Homo sapiens (Human) | 479 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0586 | inhibitor | Matthess,2010 | support | certain | ||
| experimental | MI:0424 | protein kinase assay | in vivo | Matthess,2010 | support | certain | InteractionDetection |
| experimental | MI:0113 | western blot | in vitro | Matthess,2010 | support | certain | ParticipantIdentification FeatureDetection |
| experimental | MI:1297 | phosphoamino acid analysis | Matthess,2010 | support | certain | FeatureDetection | |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Matthess,2010 | support | certain | FeatureDetection |
| experimental | MI:0424 | protein kinase assay | in vitro | Matthess,2010 | support | certain | InteractionDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (P06493) CDK1_HUMAN | PF00069
(Pkinase)
Protein kinase domain |
4 | 287 | [mitab][xml] |
Pathways
- Alzheimer disease
- Apoptosis
- Apoptosis multiple species
- C type lectin receptor signaling pathway
- Chagas disease
- Epstein Barr virus infection
- Hepatitis B
- Hepatitis C
- Herpes simplex virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- Huntington disease
- IL 17 signaling pathway
- Influenza A
- Kaposi sarcoma associated herpesvirus infection
- Legionellosis
- Lipid and atherosclerosis
- Measles
- NOD like receptor signaling pathway
- Necroptosis
- Non alcoholic fatty liver disease
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Platinum drug resistance
- RIG I like receptor signaling pathway
- Salmonella infection
- TNF signaling pathway
- Toll like receptor signaling pathway
- Toxoplasmosis
- Tuberculosis
- Viral carcinogenesis
- Viral myocarditis
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement