Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004701 | P47741 Tnfrsf4 TNR4_MOUSE |
257 | 260 | CWGNSFRTPIQEEHTDAHFT | TP | --- | Mus musculus (House mouse) | 272 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Arch,1998 | support | certain | FeatureDetection |
experimental | MI:0113 | western blot | in vitro | Arch,1998 | support | certain | ParticipantIdentification FeatureDetection |
experimental | MI:0018 | two hybrid | in vivo | Arch,1998 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q13077) TRAF1_HUMAN | IPR037306
(TNF receptor-associated factor 1, MATH domain)
TNF receptor-associated factor 1 (TRAF1) plays a role in the regulation of cell survival and apoptosis |
267 | 413 | [mitab][xml] | |
(Q12933) TRAF2_HUMAN | IPR037305
(TNF receptor-associated factor 2, MATH domain)
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis |
334 | 497 | [mitab][xml] | |
(Q13114) TRAF3_HUMAN | IPR037304
(TRAF3, MATH domain)
Tumor necrosis factor (TNF) receptor associated factor 3 (TRAF3) is a highly versatile regulator that positively controls type I interferon production, but negatively regulates mitogen-activated p... |
378 | 563 | [mitab][xml] |
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement