| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length | 
|---|---|---|---|---|---|---|---|---|
| ELMI004701 |  P47741 Tnfrsf4 TNR4_MOUSE  | 
        257 | 260 | CWGNSFRTPIQEEHTDAHFT | TP | --- | Mus musculus (House mouse) | 272 | 
  Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes | 
|---|---|---|---|---|---|---|---|
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Arch,1998 | support | certain | FeatureDetection | 
| experimental | MI:0113 | western blot | in vitro | Arch,1998 | support | certain | ParticipantIdentification FeatureDetection | 
| experimental | MI:0018 | two hybrid | in vivo | Arch,1998 | support | certain | InteractionDetection | 
  Interactions 
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes | 
|---|---|---|---|---|---|
| (Q13077) TRAF1_HUMAN |  IPR037306
                  (TNF receptor-associated factor 1, MATH domain) 
                  TNF receptor-associated factor 1 (TRAF1) plays a role in the regulation of cell survival and apoptosis  | 
             267 | 413 | [mitab][xml] | |
| (Q12933) TRAF2_HUMAN |  IPR037305
                  (TNF receptor-associated factor 2, MATH domain) 
                  TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis  | 
             334 | 497 | [mitab][xml] | |
| (Q13114) TRAF3_HUMAN |  IPR037304
                  (TRAF3, MATH domain) 
                  Tumor necrosis factor (TNF) receptor associated factor 3 (TRAF3) is a highly versatile regulator that positively controls type I interferon production, but negatively regulates mitogen-activated p...  | 
             378 | 563 | [mitab][xml] | 
    
        Please cite: 
            ELM-the Eukaryotic Linear Motif resource-2024 update.
        
    (PMID:37962385)
    
    
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
