| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI004694 | P28908 TNFRSF8 TNR8_HUMAN |
576 | 581 | LGSCSDVMLSVEEEGKEDPL | TP |
1D01 
|
Homo sapiens (Human) | 595 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Boucher,1997 | support | certain | FeatureDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Boucher,1997 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Gedrich,1996 | support | certain | FeatureDetection |
| experimental | MI:0114 | x-ray crystallography | in vitro | Ye,1999 | support | certain | InteractionDetection FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q13077) TRAF1_HUMAN | IPR037306
(TNF receptor-associated factor 1, MATH domain)
TNF receptor-associated factor 1 (TRAF1) plays a role in the regulation of cell survival and apoptosis |
267 | 413 | [mitab][xml] | |
| (Q12933) TRAF2_HUMAN | IPR037305
(TNF receptor-associated factor 2, MATH domain)
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis |
334 | 497 | [mitab][xml] |
Pathways
Please cite:
The Eukaryotic Linear Motif resource: 2022 release.
(PMID:34718738)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement