Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004694 | P28908 TNFRSF8 TNR8_HUMAN |
576 | 581 | LGSCSDVMLSVEEEGKEDPL | TP |
1D01 |
Homo sapiens (Human) | 595 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Boucher,1997 | support | certain | FeatureDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Boucher,1997 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Gedrich,1996 | support | certain | FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Ye,1999 | support | certain | InteractionDetection FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q13077) TRAF1_HUMAN | IPR037306
(TNF receptor-associated factor 1, MATH domain)
TNF receptor-associated factor 1 (TRAF1) plays a role in the regulation of cell survival and apoptosis |
267 | 413 | [mitab][xml] | |
(Q12933) TRAF2_HUMAN | IPR037305
(TNF receptor-associated factor 2, MATH domain)
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis |
334 | 497 | [mitab][xml] |
Pathways
KEGG: The sequence P28908 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement