| Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
|---|---|---|---|---|---|---|---|---|
| ELMI002133 | P07766 CD3E CD3E_HUMAN |
184 | 188 | KERPPPVPNPDYEPIRKGQR | TP |
2ROL |
Homo sapiens (Human) | 207 |
Instance evidence
| Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
|---|---|---|---|---|---|---|---|
| experimental | MI:0096 | pull down | in vivo/in vitro | Kesti,2007 | support | likely | InteractionDetection |
| experimental | MI:0084 | phage display | Kesti,2007 | support | likely | InteractionDetection | |
| experimental | MI:0081 | peptide array | Kesti,2007 | support | likely | InteractionDetection | |
| experimental | MI:0007 | anti tag coimmunoprecipitation | in vivo | Kesti,2007 | support | likely | InteractionDetection |
| experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Kesti,2007 | support | likely | FeatureDetection |
| experimental | MI:0065 | isothermal titration calorimetry | in vitro | Aitio,2008 | support | certain | InteractionDetection |
| experimental | MI:0077 | nuclear magnetic resonance | in vitro | Aitio,2008 | support | certain | InteractionDetection FeatureDetection |
| experimental | MI:0519 | glutathione s tranferase tag | in vitro | Kesti,2007 | support | certain | |
| experimental | MI:0034 | display technology | in vivo/in vitro | Kesti,2007 | support | certain | InteractionDetection |
| experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Kesti,2007 | support | certain | InteractionDetection |
| experimental | MI:0074 | mutation analysis | in vivo/in vitro | Kesti,2007 | support | certain | FeatureDetection |
Interactions
| Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
|---|---|---|---|---|---|
| (Q12929) EPS8_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
531 | 590 | [mitab][xml] | |
| (Q8TE68) ES8L1_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
478 | 537 | 24.0/24.0 | [mitab][xml] |
| (Q9H6S3) ES8L2_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
492 | 551 | [mitab][xml] | |
| (Q8TE67) ES8L3_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
450 | 509 | [mitab][xml] | |
| (P16333) NCK1_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
2 | 61 | 8.2/8.4 | [mitab][xml] |
| (O43639) NCK2_HUMAN | IPR001452
(SH3 domain)
SH3 (src Homology-3) domains are small protein modules containing approximately 50 amino acid residues |
2 | 61 | [mitab][xml] |
Pathways
- Chagas disease
- Epstein Barr virus infection
- Hematopoietic cell lineage
- Human T cell leukemia virus 1 infection
- Human immunodeficiency virus 1 infection
- Measles
- PD L1 expression and PD 1 checkpoint pathway in cancer
- Primary immunodeficiency
- T cell receptor signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement