The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002590 P10636-8 MAPT
TAU_HUMAN
213 219 GSRSRTPSLPTPPTREPKKV TP --- Homo sapiens (Human) 441

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Reynolds,2008 support likely
experimental MI:0074 mutation analysis in vivo/in vitro Reynolds,2008 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P39688) FYN_MOUSE PF00018 (SH3_1)
SH3 domain
88 135 135.0/135.0 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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