The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002584 O55207 Synj2
SYNJ2_RAT
1120 1125 VPNRPRPPHPPQRPPPPTGL TP --- Rattus norvegicus (Norway rat) 1496

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0004 affinity chromatography technology in vivo/in vitro Nemoto,2001 support certain InteractionDetection
experimental MI:0047 far western blotting in vitro Nemoto,2001 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Nemoto,2001 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Nemoto,2001 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(O08838) AMPH_RAT PF14604 (SH3_9)
Variant SH3 domain
617 680 [mitab][xml]
(O08839) BIN1_RAT PF14604 (SH3_9)
Variant SH3 domain
522 585 [mitab][xml]
(O35964) SH3G1_RAT PF00018 (SH3_1)
SH3 domain
312 357 [mitab][xml]
(O35179) SH3G2_RAT PF14604 (SH3_9)
Variant SH3 domain
297 345 [mitab][xml]
(O35180) SH3G3_RAT PF14604 (SH3_9)
Variant SH3 domain
293 340 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence O55207 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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