The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003696 Q06124 PTPN11
PTN11_HUMAN
584 587 MREDSARVYENVGLMQQQKS TP --- Homo sapiens (Human) 597

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0074 mutation analysis in vivo/in vitro Vogel,1996 support certain FeatureDetection
experimental MI:0113 western blot in vitro Vogel,1996 support certain ParticipantIdentification FeatureDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Vogel,1996 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62993) GRB2_HUMAN PF00017 (SH2)
SH2 domain
60 135 [mitab][xml]

o  Pathways

KEGG: The sequence Q06124 is implicated in the following 11 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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