The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001515 Q14209 E2F2
E2F2_HUMAN
420 428 GLEAGEGISDLFDSYDLGDL TP 1N4M  
pdb:1N4M
Homo sapiens (Human) 437

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0114 x-ray crystallography in vitro Lee,2002 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lee,2002 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lee,2002 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P06400) RB_HUMAN PF01858 (RB_A)
Retinoblastoma-associated protein A domain
373 573 [mitab][xml]
(P06400) RB_HUMAN PF01857 (RB_B)
Retinoblastoma-associated protein B domain
645 766 [mitab][xml]

o  Pathways

KEGG: The sequence Q14209 is implicated in the following 13 Pathways: (color codes: This sequence=red, interacting sequence=orange) Reactome: The sequence Q14209 is implicated in the following 13 Pathways:
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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