The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001576 P35222 CTNNB1
CTNB1_HUMAN
776 781 LMDGLPPGDSNQLAWFDTDL TP 3DIW  
pdb:3DIW
Homo sapiens (Human) 781

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Zhang,2008 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Zhang,2008 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9DBG9) TX1B3_MOUSE PF00595 (PDZ)
PDZ domain (Also known as DHR or GLGF)
17 110 0.14/0.24 [mitab][xml]

o  Switches



This ELM instance is part of the following 2 switching mechanisms annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P35222 is implicated in the following 21 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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