The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000799 P52701 MSH6
MSH6_HUMAN
4 13 MSRQSTLYSFFPKSPALSDA TP --- Homo sapiens (Human) 1360

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0107 surface plasmon resonance in vitro Prestel,2019 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Clark,2000 support certain FeatureDetection
experimental MI:0096 pull down in vivo/in vitro Clark,2000 support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Clark,2000 support certain
not annotated not specified Warbrick,2000 not specified not specified

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 2.95/3.05 [mitab][xml]

o  Pathways

KEGG: The sequence P52701 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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