The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI000792 P39748 FEN1
FEN1_HUMAN
337 346 RQGSTQGRLDDFFKVTGSLS TP 1U7B  
pdb:1U7B 1UL1  
Homo sapiens (Human) 380

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Bruning,2004 support certain InteractionDetection
experimental MI:0107 surface plasmon resonance in vitro Watanabe,1987 support certain InteractionDetection FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Wilson,2017 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Sakurai,2005 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Bruning,2004 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Warbrick,1997 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P12004) PCNA_HUMAN PF02747 (PCNA_C)
Proliferating cell nuclear antigen, C-terminal domain
127 254 59.9/59.9 [mitab][xml]

o  Pathways

KEGG: The sequence P39748 is implicated in the following 3 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The Eukaryotic Linear Motif resource: 2022 release. (PMID:34718738)

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