The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002503 Q9HCJ0 TNRC6C
TNR6C_HUMAN
1385 1398 SINWPPEFHPGVPWKGLQNI TP 2X04  
pdb:2X04 3KTP  
pdb:3KTP
Homo sapiens (Human) 1690

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Jinek,2010 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Fabian,2009 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Fabian,2009 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Fabian,2009 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Fabian,2009 support certain FeatureDetection
experimental MI:0007 anti tag coimmunoprecipitation in vivo Huntzinger,2010 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Huntzinger,2010 support certain FeatureDetection
experimental MI:0065 isothermal titration calorimetry in vitro Kozlov,2010 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Kozlov,2010 support certain InteractionDetection FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Kozlov,2010 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Kozlov,2010 support certain InteractionDetection FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Jinek,2010 support certain FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Jinek,2010 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P11940) PABP1_HUMAN PF00658 (PABP)
Poly-adenylate binding protein, unique domain
543 614 [mitab][xml]
Please cite: ELM 2016-data update and new functionality of the eukaryotic linear motif resource. (PMID:26615199)

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