Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI004528 | Q03164 MLL MLL1_HUMAN |
129 | 151 | FRAVFGESGGGGGSGEDEQFLGF | TP |
2MSR 2MTN 3U88 |
Homo sapiens (Human) | 3969 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Huang,2012 | support | certain | InteractionDetection |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Huang,2012 | support | certain | FeatureDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Huang,2012 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0405 | competition binding | in vitro | Murai,2014 | support | certain | InteractionDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Murai,2014 | support | certain | InteractionDetection |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Murai,2014 | support | certain | FeatureDetection |
experimental | MI:0077 | nuclear magnetic resonance | in vitro | Murai,2014 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0905 | amplified luminescent proximity homogeneous assay | Sharma,2018 | support | certain | InteractionDetection | |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Sharma,2018 | support | certain | FeatureDetection |
experimental | MI:0405 | competition binding | in vitro | Cermakova,2014 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Cermakova,2014 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Cermakova,2014 | support | certain | InteractionDetection |
experimental | MI:0077 | nuclear magnetic resonance | in vitro | Cermakova,2014 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0905 | amplified luminescent proximity homogeneous assay | Cermakova,2014 | support | certain | InteractionDetection | |
experimental | MI:0074 | mutation analysis | in vivo/in vitro | Cermakova,2014 | support | certain | FeatureDetection |
experimental | MI:0019 | coimmunoprecipitation | in vivo/in vitro | Cermakova,2014 | support | certain | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(O75475) PSIP1_HUMAN | IPR021567
(Lens epithelium-derived growth factor, integrase-binding domain)
Lens epithelium-derived growth factor (LEDGF), also known as transcriptional co-activator p75, is a chromatin-associated protein that protects cells from stress-induced apoptosis |
349 | 449 | 0.47/0.47 | [mitab][xml] |
Pathways
KEGG: The sequence Q03164 is implicated in the following 4 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement