The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI004918 P02751 FN1
FINC_HUMAN
1615 1619 YVVSVYAQNPSGESQPLVQT TP 4MMX  
Homo sapiens (Human) 2386

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:1088 phenotype-based detection assay Chen,1996 support certain InteractionDetection
experimental MI:0411 elisa in vitro Ozawa,2016 support certain InteractionDetection ParticipantIdentification
experimental MI:0411 elisa in vitro Jovanovic,2007 support certain InteractionDetection ParticipantIdentification
experimental MI:0107 surface plasmon resonance in vitro Jovanovic,2007 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Van Agthoven,2014 support certain InteractionDetection FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P08648) ITA5_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
326 368 0.0108/0.0108 [mitab][xml]
(P06756) ITAV_HUMAN PF01839 (FG-GAP)
FG-GAP repeat
252 286 0.18/0.18 [mitab][xml]
(P05556) ITB1_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
138 382 0.0108/0.0108 [mitab][xml]
(P05106) ITB3_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
133 381 [mitab][xml]
(P18084) ITB5_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
133 382 [mitab][xml]
(P18564) ITB6_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
128 375 0.18/0.18 [mitab][xml]
(P26012) ITB8_HUMAN PF00362 (Integrin_beta)
Integrin, beta chain
142 388 [mitab][xml]

o  Pathways

KEGG: The sequence P02751 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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