The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002467 Q8WUM4 PDCD6IP
PDC6I_HUMAN
797 807 APPPQAQGPPYPTYPGYPGY TP 3E1R  
pdb:3E1R
Homo sapiens (Human) 868

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Lee,2008 support certain
experimental MI:0007 anti tag coimmunoprecipitation in vivo Morita,2007 support certain InteractionDetection
experimental MI:0018 two hybrid in vivo Morita,2007 support certain InteractionDetection
experimental MI:0403 colocalization in vitro Morita,2007 support certain
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Morita,2007 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Morita,2007 support certain FeatureDetection
experimental MI:0027 cosedimentation in vitro Lee,2008 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Lee,2008 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Lee,2008 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Lee,2008 support certain FeatureDetection
experimental MI:0107 surface plasmon resonance in vitro Lee,2008 support certain InteractionDetection FeatureDetection
experimental MI:0114 x-ray crystallography in vitro Lee,2008 support certain InteractionDetection FeatureDetection
experimental MI:0728 gal4 vp16 complementation in vitro Iwamori,2010 support certain InteractionDetection
experimental MI:0405 competition binding in vitro Iwamori,2010 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q53EZ4) CEP55_HUMAN PF12180 (EABR)
TSG101 and ALIX binding domain of CEP55
171 205 1.5/1.5 [mitab][xml]

o  Pathways

KEGG: The sequence Q8WUM4 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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