The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001874 P04774 Scn1a
SCN1A_RAT
1916 1935 EVSAVIIQRAYRRHLLKRTV TP --- Rattus norvegicus (Norway rat) 2009

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Gaudioso,2011 support certain
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Gaudioso,2011 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Gaudioso,2011 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P62161) CALM_RAT PF13499 (EF_hand_7)
EF-hand domain pair
8 73 [mitab][xml]
(P62161) CALM_RAT PF13499 (EF_hand_7)
EF-hand domain pair
85 146 [mitab][xml]

o  Pathways

KEGG: The sequence P04774 is implicated in the following 1 Pathway: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
feedback@elm.eu.org