The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003200 Q07813 Bax
BAX_MOUSE
55 71 ASTKKLSECLRRIGDELDSN TP 2XA0  
Mus musculus (House mouse) 192

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0065 isothermal titration calorimetry in vitro Ku,2011 support certain InteractionDetection
experimental MI:0114 x-ray crystallography in vitro Ku,2011 support certain InteractionDetection FeatureDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Ku,2011 support certain FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P10415) BCL2_HUMAN PF00452 (Bcl-2)
Apoptosis regulator proteins, Bcl-2 family
97 195 13.15/17.05 [mitab][xml]

o  Pathways

KEGG: The sequence Q07813 is implicated in the following 48 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: ELM-the Eukaryotic Linear Motif resource-2024 update. (PMID:37962385)

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