Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003200 | Q07813 Bax BAX_MOUSE |
55 | 71 | ASTKKLSECLRRIGDELDSN | TP |
2XA0 |
Mus musculus (House mouse) | 192 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0065 | isothermal titration calorimetry | in vitro | Ku,2011 | support | certain | InteractionDetection |
experimental | MI:0114 | x-ray crystallography | in vitro | Ku,2011 | support | certain | InteractionDetection FeatureDetection |
experimental | MI:0005 | alanine scanning | in vivo/in vitro/in silico | Ku,2011 | support | certain | FeatureDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(P10415) BCL2_HUMAN | PF00452
(Bcl-2)
Apoptosis regulator proteins, Bcl-2 family |
97 | 195 | 13.15/17.05 | [mitab][xml] |
Pathways
KEGG: The sequence Q07813 is implicated in the following 48 Pathways: (color codes: This sequence=red, interacting sequence=orange)- AGE RAGE signaling pathway in diabetic complications
- Amyotrophic lateral sclerosis
- Apoptosis
- Apoptosis multiple species
- Basal cell carcinoma
- Breast cancer
- Chronic myeloid leukemia
- Colorectal cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- Gastric cancer
- Glioma
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Herpes simplex virus 1 infection
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Human papillomavirus infection
- Huntington disease
- Influenza A
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- Longevity regulating pathway
- Measles
- Melanoma
- Necroptosis
- Neurotrophin signaling pathway
- Non alcoholic fatty liver disease
- Non small cell lung cancer
- Pancreatic cancer
- Parkinson disease
- Pathways in cancer
- Pathways of neurodegeneration multiple diseases
- Platinum drug resistance
- Prion disease
- Protein processing in endoplasmic reticulum
- Salmonella infection
- Small cell lung cancer
- Sphingolipid signaling pathway
- Thyroid cancer
- Transcriptional misregulation in cancer
- Tuberculosis
- Viral carcinogenesis
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement