The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI001964 P35222 CTNNB1
CTNB1_HUMAN
243 248 GIPALVKMLGSPVDSVLFYA TP --- Homo sapiens (Human) 781

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support likely InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Ryo,2001 support likely
experimental MI:0434 phosphatase assay in vitro Ryo,2001 support likely InteractionDetection
experimental MI:0019 coimmunoprecipitation in vivo/in vitro Ryo,2001 support likely InteractionDetection
experimental MI:0005 alanine scanning in vivo/in vitro/in silico Ryo,2001 support likely FeatureDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q9QUR7) PIN1_MOUSE PF00397 (WW)
WW domain
7 37 [mitab][xml]

o  Switches



This ELM instance is part of the following 1 switching mechanism annotated at the switches.ELM resource:

o  Pathways

KEGG: The sequence P35222 is implicated in the following 21 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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