The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI003680 P04637 TP53
P53_HUMAN
382 386 GQSTSRHKKLMFKTEGPDSD U --- Homo sapiens (Human) 393

o  Instance evidence

Evidence classPSMI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0586 inhibitor Ma,2010 support not specified
experimental MI:0997 ubiquitinase assay in vitro Ma,2010 support not specified InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Ma,2010 support not specified
experimental MI:0096 pull down in vivo/in vitro Ma,2010 support not specified InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(Q93009) UBP7_HUMAN PF12436 (USP7_ICP0_bdg)
ICP0-binding domain of Ubiquitin-specific protease 7
620 865 [mitab][xml]

o  Pathways

KEGG: The sequence P04637 is implicated in the following 35 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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