Accession | Acc. Gene-, Name | Start | End | Subsequence | Logic | PDB | Organism | Length |
---|---|---|---|---|---|---|---|---|
ELMI003680 | P04637 TP53 P53_HUMAN |
382 | 386 | GQSTSRHKKLMFKTEGPDSD | U | --- | Homo sapiens (Human) | 393 |
Instance evidence
Evidence class | PSI-MI | Method | BioSource | PubMed | Logic | Reliability | Notes |
---|---|---|---|---|---|---|---|
experimental | MI:0586 | inhibitor | Ma,2010 | support | not specified | ||
experimental | MI:0997 | ubiquitinase assay | in vitro | Ma,2010 | support | not specified | InteractionDetection |
experimental | MI:0519 | glutathione s tranferase tag | in vitro | Ma,2010 | support | not specified | |
experimental | MI:0096 | pull down | in vivo/in vitro | Ma,2010 | support | not specified | InteractionDetection |
Interactions
Uniprot Id | Domain family | Domain Start | Domain End | Affinity Min/Max (µMol) | Notes |
---|---|---|---|---|---|
(Q93009) UBP7_HUMAN | PF12436
(USP7_ICP0_bdg)
ICP0-binding domain of Ubiquitin-specific protease 7 |
620 | 865 | [mitab][xml] |
Pathways
KEGG: The sequence P04637 is implicated in the following 51 Pathways: (color codes: This sequence=red, interacting sequence=orange)- Amyotrophic lateral sclerosis
- Apoptosis
- Basal cell carcinoma
- Bladder cancer
- Breast cancer
- Cell cycle
- Cellular senescence
- Central carbon metabolism in cancer
- Chronic myeloid leukemia
- Colorectal cancer
- Endocrine resistance
- Endometrial cancer
- Epstein Barr virus infection
- Ferroptosis
- Fluid shear stress and atherosclerosis
- Gastric cancer
- Glioma
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Herpes simplex virus 1 infection
- Human T cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human papillomavirus infection
- Huntington disease
- Kaposi sarcoma associated herpesvirus infection
- Lipid and atherosclerosis
- Longevity regulating pathway
- MAPK signaling pathway
- Measles
- Melanoma
- MicroRNAs in cancer
- Mitophagy animal
- Neurotrophin signaling pathway
- Non small cell lung cancer
- PI3K Akt signaling pathway
- Pancreatic cancer
- Parkinson disease
- Pathways in cancer
- Platinum drug resistance
- Prostate cancer
- Proteoglycans in cancer
- Shigellosis
- Small cell lung cancer
- Sphingolipid signaling pathway
- Thyroid cancer
- Thyroid hormone signaling pathway
- Transcriptional misregulation in cancer
- Viral carcinogenesis
- Wnt signaling pathway
- p53 signaling pathway
Please cite:
ELM-the Eukaryotic Linear Motif resource-2024 update.
(PMID:37962385)
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement
ELM data can be downloaded & distributed for non-commercial use according to the ELM Software License Agreement