The Eukaryotic Linear Motif resource for
Functional Sites in Proteins

o  Instance

Accession Acc. Gene-, NameStartEndSubsequenceLogic PDB OrganismLength
ELMI002687 O95644 NFATC1
NFAC1_HUMAN
387 390 KGGFCDQYLAVPQHPYQWAK TP --- Homo sapiens (Human) 943

o  Instance evidence

Evidence classPSI-MIMethodBioSourcePubMedLogicReliabilityNotes
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Rodriguez,2009 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Park,2000 support certain
experimental MI:0096 pull down in vivo/in vitro support certain InteractionDetection
experimental MI:0519 glutathione s tranferase tag in vitro Martinez-Martinez,2006 support certain
experimental MI:0405 competition binding in vitro Martinez-Martinez,2006 support certain InteractionDetection
experimental MI:0077 nuclear magnetic resonance in vitro Park,2000 support certain InteractionDetection FeatureDetection
experimental MI:0506 over expressed level in vivo Park,2000 support certain
experimental MI:0405 competition binding in vitro Park,2000 support certain InteractionDetection
experimental MI:0065 isothermal titration calorimetry in vitro Park,2000 support certain InteractionDetection
experimental MI:0074 mutation analysis in vivo/in vitro Park,2000 support certain FeatureDetection
experimental MI:0074 mutation analysis in vivo/in vitro Rodriguez,2009 support certain FeatureDetection
experimental MI:0405 competition binding in vitro Rodriguez,2009 support certain InteractionDetection

o  Interactions

Uniprot Id Domain family Domain Start Domain End Affinity Min/Max (µMol) Notes
(P63098) CANB1_HUMAN PF13499 (EF_hand_7)
EF-hand domain pair
1.3/1.3 [mitab][xml]
(Q08209) PP2BA_HUMAN PF00149 (Metallophos)
Calcineurin-like phosphoesterase
83 285 1.3/1.3 [mitab][xml]

o  Pathways

KEGG: The sequence O95644 is implicated in the following 12 Pathways: (color codes: This sequence=red, interacting sequence=orange)
Please cite: The eukaryotic linear motif resource - 2018 update. (PMID:29136216)

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